The midfielder was forced off early into the second-half for Senegal in their friendly against Brazil due to injury. Sarr was accompanied by medics as he was helped from the pitch on Saturday.
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Tottenham are waiting on an update, though his absence would prove a blow for manager Thomas Frank.
Spurs had captain Cristian Romero and loanee striker Randal Kolo Muani collect injuries during the 2-2 draw with Manchester United last weekend.
Mohammed Kudus also missed that game after picking up a knock the week before.