The £125m signing struck in Liverpool's 2-1 Carabao Cup win against Southampton.
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Isak remarked afterwards: "Amazing. It was good to get back out there and score my first goal here, at Anfield. The win as well. So, it's a good night.
"I should have scored that one (the chance early on) as well, but that's a part of being a striker – you miss some and then you score some.
"I think the most important is to shake it off and to be ready for the next one.
"I just try to play my game and not think too much. I feel confidence in myself that things will work out and that when I get my chances I'll put them away – that's my mindset. I'm happy that I put one away today."