Spurs tried to sign the fleet-footed Brazilian last summer when Thomas Frank was in charge, but Pep Guardiola wanted to keep him as part of his squad.
Guardiola's imminent departure will bring several changes behind the scenes, and according to the Daily Mail, Tottenham want to rekindle their interest in the 22-year-old.
A £60 million transfer fee has been suggested for Savinho, whose contract at the Etihad Stadium doesn't expire until June 2031.
Savinho suffered from multiple injury troubles throughout the 2025/26 campaign, while other stars being ahead of him in the pecking order meant he only started seven Premier League games.
Regular starts would be guaranteed under Roberto De Zerbi next term, however, and Tottenham could finally land the talented winger.
John Stones has previously hailed Savinho as "incredible" after scoring in the 3-1 FA Cup victory over Newcastle United in March.