Spain are among the favourites to win the tournament in the United States, Mexico and Canada, with De la Fuente proving he isn't afraid to make big decisions.
The 2010 winners have left out Real Madrid defenders Dani Carvajal and Dean Huijsen following their difficult campaigns at club level.
In fact, this is the first time in the competition's history that Spain's World Cup squad hasn't featured a single Real player.
Barcelona, meanwhile, have eight representatives from their La Liga-winning side, including Joan Garcia, Eric Garcia, Pau Cubarsi, Gavi, Pedri, Dani Olmo, Ferran Torres and Lamine Yamal.
Spain's 26-man squad for the 2026 World Cup
Goalkeepers: Unai Simón, David Raya, Joan García
Defenders: Marc Cucurella, Alejandro Grimaldo, Pau Cubarsí, Aymeric Laporte, Marc Pubill, Eric García, Marcos Llorente, Pedro Porro
Midfielders: Pedri, Fabián Ruiz, Martín Zubimendi, Gavi, Rodrigo Hernández, Álex Baena, Mikel Merino, Mikel Oyarzabal
Forwards: Dani Olmo, Nico Williams, Yeremy Pino, Ferran Torres, Borja Iglesias, Víctor Muñoz, Lamine Yamal