Jacobo Ortega, Adri Pérez, Jaime Barroso and Diego Aguado struck the goals for the visitors.
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Real Madrid now sit top of the table with 12 points from four games, so boasting a 100 per cent record.
The result could've been more for Real as Jacobo also struck one effort against the Liverpool crossbar.
Featuring for Liverpool was centre-back Prince Cisse, the son of former Reds striker Djibril Cisse.
