The Portuguese was named new Hammers manager on Saturday, succeeding Graham Potter after he was sacked in the morning.
Nuno says he and his incoming staff know plenty about West Ham's squad thanks to facing the Irons over the years in the Premier League.
He told the club's website: “We know each other, like I said to you before. It’s been many years. We faced (each other) many, many times. We know each other, even as opponents. Like you say (I worked with) Max (Kilman), but now it’s a new beginning for everybody. It’s a new process that we really have to know, and we find out who we are and what we want to be.
“First of all, we have to realise who we are, and then we can create an identity. But first of all, we have to know each other really, really well.
"I want to integrate myself, first of all, in the Club, with you (the staff), with all the people here, because we have to become as a family. We have to realise that we are the ones that represent the community. The community sees us as a mirror, as an image that they want to (be), so that’s why we have to make strong values. We have to be respectful to each other.”
Nuno added, “The supporters are very important, very important. That’s why I truly believe what we want to achieve is a platform to be able (to build from). Now is not the moment to ask the fans. Now is the moment to deliver to the fans. I think we have to give them, so then they can give us back.
“When we have this bond, when other teams come to play against us, it’s going to be hell. But we have to achieve this bond first. We have protect each other, all of us inside of the building, the fans, everybody. Everybody that really cares about West Ham has to protect each other.”