With the Sweden striker pushing to leave for Liverpool, Isak has privately declared he has played his last game for the club.
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For the moment, Newcastle haven't taken disciplinary action against Isak, but that will change if he fails to appear for their opening Premier League game against Aston Villa.
Isak won't be considered for selection, but will be expected to attend to match.
The Daily Mail says should Isak fail to appear, Newcastle will take action, which will include a heavy fine.