The Brazil striker is a doubt after suffering an injury which saw him miss Saturday's event to switch on the Christmas lights in Altrincham.
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VisitAltrincham posted on social media: "Unfortunately, Matheus Cunha has had an accident in training today and will not be able to attend tonight's Christmas Lights Switch on in Altrincham due to medical reasons."
However, ESPN is reporting Cunha collected only a "minor knock", so suggesting it won't be enough to rule him out tomorrow night.
United will need Cunha, with fellow striker Benjamin Sesko missing until mid-December with a knee injury.