The Holland defender had played every minute of Premier League action and coming on as a substitute in the Carabao Cup tie against Grimsby Town.
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"It's hard because, if you see that position, especially this year, it's just Harry (Maguire) and Matta playing those positions," Amorim told Premier League Productions.
"It is a blow. He is playing really really well. But I'm really excited with Ayden (Heaven). He is working there. I think he has the right characteristics to play there.
"It is a big opportunity for everyone to see Ayden.
"For Matta, it is a small thing. I expect to have Matthijs next game (at Wolves)."