The Athletic says United have reached an agreement with Bayern for De Ligt.
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The English giants will pay a transfer fee of €45m, plus €5m in bonuses.
De Ligt will sign a contract that runs until the summer of 2029, with an option for another year, once he passes his medical.
Bayern have also accepted United's bid for Mazraoui.
The right-back will vost 15 million euros (172 million kroner), as well as another 5 million euros in bonuses.
Mazraoui is also expected to sign a five-year contract, with an option for another year.