Liverpool signed Isak last summer for a transfer fee of €145M in a deal that is yet to pay off after the Swedish striker missed pre-season and picked up an injury leaving him out of action for a number of months.
He has scored just three goals in 16 appearances for his new club whilst Kane 48 goals in 40 appearances for Bayern in what has been another incredible season.
The England captain is showing no sign of slowing down and Hoeness was asked by Kicker about his future heading into the summer transfer window.
"(Kane) didn't exercise his release clause, which means he's definitely under contract here until summer 2027.
"What I'm hearing and feeling is that he and his family feel extremely comfortable here. You never know when a Saudi comes along and puts a lot of money on the table, but he feels very much at home."
"I'd say Harry Kane is worth €150m (£130m). But then you see Alexander Isak cost €150m to Liverpool. If Isak is worth 150m, then Harry is worth €250m (£217m)."
The 32-year-old remains under contract until the end of next season and does not look likely to leave this summer despite links to top sides such as Manchester United.
The Sun report Bayern fear that Kane could be tempted by a massive offer from Saudi Arabia which, as he comes to the end of his career, could be tempting.