Fulham won 2-1 at Tottenham Hotspur stadium, with Kenny Tete and Harry Wilson scoring inside the first six minutes before Mohammed Kudus just before the hour.
Asked if the players are following his instructions, Frank insisted: "No, I am not (worried), because I think we have seen clearly other times it has worked much better. Maybe we haven’t been absolutely free-floating, but it looked much better. I think it is isolated in two different games. The Arsenal game was hopefully a big one-off in terms of the overall performance.
"I think PSG it looked like they took on board my messages it is fair to say and second half, it looks like they took on my messages. And I think this game we are behind 2-0 down after six minutes with all the nice, good questions that we want to do so well to get back on track. I think there are so many things into it."
On if the connection with the fans is lapsing, the Dane also stated: "I think there's nothing that the players, I, everyone want to get the win here. Nothing we want more. And I hope the fans can see that they were running out there today, giving everything. But football is so beautiful and complex.
"It's 11 players that need to be in sync and play and run at the same time. And there are small setbacks during games, you need to get through it and stick to the plan, stick to the bits. And sometimes it's just more tough.
"And sometimes you're in a spell where it's difficult, which it is right now. But there's only one way, it's going forward and do everything you can to get out of it together. So there's only one thing, we keep going and do everything we can to win the next home game."