Spurs won 2-0 via goals from Richarlison and Xavi Simons.
Andrews said afterwards, "I'm disappointed, clearly. It's a game we came into feeling we could absolutely compete and get a result from - the players' confidence levels were pretty high.
"The reality is that we didn't perform in the first half, and we have to own that. We'll search for the reasons as to why that was.
"The league is so demanding - the individuals that you come up against, what you do with and without the ball, etc. - you have to be at a certain level to compete in this league and we weren't quite there.
"Our lads have been immense all season, our performance levels have been consistent as we look to grow this team and take a new step. Today, we didn't hit the levels that we've become consistent with."