It was only the third-youngest selection for any Premier League club, behind only Middlesbrough's team against Fulham in May 2006 (20 years 181 days) and Arsenal's line-up for their May 2009 meeting with Portsmouth (22 years 237 days).
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Chido Obi also became United's youngest starter in a Premier League match, at the age of 17 years and 156 days. The previous record holder was Mason Greenwood, at 17 years and 223 days.
Also starting for the 4-3 defeat on Sunday were Harry Amass, Tyler Fredricson and Patrick Dorgu.
Amorim made his selection with an eye on Thursday's Europa League second-leg of their semifinal against Athletic Bilbao.