The 33-year-old has already announced he will leave Man United as a free agent once his contract expires at the end of the season.
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According to The Sun, Inter Miami are looking to bring Casemiro to the MLS to join up with former rival Messi.
The report adds that the Man United midfielder and his wife Anna have been spotted in Miami as he weighs up his next move.
If he joins the club, Casemiro would become the 28th player to play with Cristiano Ronaldo and Messi.