The 29-year-old moved to the 2025-26 Ligue 1 title challengers in February following a disappointing spell with Mexican side Club America.
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Saint-Maximin managed to rediscover some form for Lens, scoring four goals and providing three assists in his 13 games.
According to L’Équipe, the former Newcastle man could be on the move yet again as MLS side Charlotte FC open talks.
Currently sixth in the Eastern Conference table Charlotte FC are looking to snap Saint-Maximin as a free agent with his Lens contract set to expire in June.