The 2-1 loss was greatest in terms of the gap between teams in the football pyramid in the FA Cup.
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Glasner said afterwards: "We give congratulations to Macclesfield for winning.
"We had no kind of quality today and I saw no one who could win a dribble. Then conceding set goals and timing in the header.
"If you can't create clear chances, it is a lack of quality that we have shown today. We deserved to lose."
On his hopes after making changes at half-time, he added: "Quality. From everyone. Honestly, I have no explanation for what I have seen today and we can find excuses but you don't need tactics and a manager for these games.
"So I think if you just show what you are capable of and show pride then you perform in a different way."